Recombination between Vaccine and Field Strains of Porcine Reproductive and Respiratory Syndrome Virus

We isolated and plaque purified IA76950-WT and IA70388-R, 2 porcine reproductive and respiratory syndrome viruses from pigs in the same herd in Iowa, USA, that exhibited coughing and had interstitial pneumonia. Phylogenetic and molecular evolutionary analysis indicated that IA70388-R is a natural recombinant from Fostera PRRSV vaccine and field strain IA76950-WT.

Wang A, Chen Q, Wang L, Madson D, Harmon K, Gauger P, Zhang J, Li G. Recombination between vaccine and field strains of porcine reproductive and respiratory syndrome virus. Emerg Infect Dis. 2019 Dec. https://dx.doi.org/10.3201/eid2512.191111