Dealing with unexpected Actinobacillus pleuropneumoniae serological results

Andr? Broes, DVM, PhD, Diplomate ECPHM; Guy-Pierre Martineau, DVM, Diplomate ECPHM; Marcelo Gottschalk, DVM, PhD

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Serological testing is widely used to monitor swine herds for Actinobacillus pleuropneumoniae (APP). Several serological tests are presently used, most often the complement fixation test, the long-chain lipopolysaccharide enzyme-linked immunosorbent assay (ELISA), and the ApxIV ELISA. Serological testing occasionally generates ambiguous results. In such situations, bacterial isolation and polymerase chain reaction testing must be used in order to accurately define the presence or absence of APP. Examples of unexpected serological results and the eventual means of establishing herd APP status are illustrated by means of 10 cases that occurred in European and North American herds.

Keywords: Actinobacillus pleuropneumoniae, enzyme-linked immunosorbent assay, polymerase chain reaction

RIS citationCite as: Broes A, Martineau GP, Gottschalk M. Dealing with unexpected Actinobacillus pleuropneumoniae serological results. J Swine Health Prod 2007;15(5):264-269.

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