TY - JOUR AU - Sturos, MJ AU - Robbins, RC AU - Moreno, R TI - Narasin toxicosis in finishing pigs T2 - Journal of Swine Health and Production JF - Journal of Swine Health and Production J2 - JSHAP SN - 1537-209X DP - American Association of Swine Veterinarians PB - American Association of Swine Veterinarians DA - 2016/Jul// PY - 2016 VL - 24 M1 - 4 IS - 4 M2 - 205 SP - 205-211 L2 - https://www.aasv.org/shap/issues/v24n4/v24n4p205.html UR - https://www.aasv.org/shap/abstracts/abstract.php?v24n4p205 L1 - https://www.aasv.org/shap/issues/v24n4/v24n4p205.pdf KW - swine KW - narasin KW - toxicity KW - finisher pigs N2 - This case report documents a clinical case of narasin toxicosis in a group of 19-week-old finisher pigs caused by accidental overdose of narasin in the feed at concentrations varying from 139 ppm (139 g per tonne) to 645 ppm (645 g per tonne). Affected pigs exhibited anorexia, pain (vocalization), skeletal muscle weakness, ataxia, recumbency, and dyspnea. Pathological lesions in the affected pigs examined were primarily restricted to skeletal muscle degeneration and necrosis. Skeletal muscles that were most severely affected included the diaphragm and outer muscularis layer of the proximal esophagus. Of the 3000 exposed pigs, 86 pigs died and 415 pigs were euthanized for animal welfare reasons. The overdose was caused by a broken load cell allowing undetected continuous leakage of narasin within the micro-ingredient batching system at the feed mill. Corrective action was implemented at the feed mill to prevent further episodes. ER -